[MMTK] Re: MMTK questions

khinsen at cea.fr khinsen at cea.fr
Mon Aug 1 17:08:50 CEST 2005


On Jul 29, 2005, at 18:09, Matias Saavedra wrote:

> Modes analysis... the results of the second analysis,
> in terms of deformations energies or amplitudes, are
> comparable to the results of the first one? I ask that

Yes.

> because i know that deformation energies and
> amplitudes of movement are system-dependent
> (qualitative), and can not be directly compared
> between diferent systems (proteins)... but what about

Deformation energies can be compared between proteins. Amplitudes can 
be as well, though I don't know any application where that would be 
useful.

> 2) Can i use the minimized protein to make a single
> mutation and then perform directly a new Normal Modes
> analysis without the need of a new minimization step?

No. Didn't we already discuss this?

Konrad.
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Konrad Hinsen
Laboratoire Léon Brillouin, CEA Saclay,
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E-Mail: khinsen at cea.fr
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